Functional and Anatomical Imaging Research

Members

Description

POSITRON EMISSION TOMOGRAPHY

  • Development and validation of compartmental models to quantify physiological information
  • Spectral Analysis methods
  • Development of population and Bayesian approaches for quantitative brain imaging
  • Imaging genomics: integration of functional images of receptor density with brain mRNA
  • Development of methods for voxel-wise quantification
  • Arterial input function modeling studies
  • Application of models and methods for the quantification of PET data in different systems of interest as, for instance: microglia activation in healthy subjects and patients affected by schizophrenia (targeted with [11C]PBR28), cerebral protein synthesis (L-[1-11C]leucine), proliferation ([11C]FLT), glucose metabolism ([18F]FDG), acetylcholinesterase activity ([11C]MP4A), receptor studies: dopaminergic, serotoninergic, adenosinergic, opioid and GABAergic systems targeted with [11C]FLB457, [11C]befloxatone, [11C]WAY100635, [11C]MDL100907, [11C]SCH442246, [11C]DPN, [11C]Ro15-4513.

MAGNETIC RESONANCE IMAGING

  • Quantitative analysis of dynamic susceptibility contrast-enhanced MR images, DSC-MRI
  • Deconvolution methods for perfusion quantification from Arterial Spin Labeling
  • Arterial Spin Labelling MRI pulse sequence developing and modelling
  • Functional and effective connectivity from fMRI in resting state
  • Susceptibility Weighted Imaging and Quantitative Susceptibility Mapping (QSM)
  • Multi Shells DTI
  • Lesion detection from DIR and FLAIR images

ULTRASOUND IMAGES

  • Development of methods for the kinetic analysis of ultrasound images

Website http://bio.dei.unipd.it/fair/